Retinal specialists inject an ever increasing number of medicines into patient's eyes (Amphoterecin, Kenalog, Macugen, Avastin, Lucentis, etc). These various medications have been extremely helpful in the management of many diseases such as macular degeneration, diabetes, infections and retinal vein occlusions. Techniques and anaesthetic agents have improved dramatically over the years...making the procedure much less uncomfortable than most patients fear.Saturday, July 25, 2009
What are the risks of an injection into the eye?
Retinal specialists inject an ever increasing number of medicines into patient's eyes (Amphoterecin, Kenalog, Macugen, Avastin, Lucentis, etc). These various medications have been extremely helpful in the management of many diseases such as macular degeneration, diabetes, infections and retinal vein occlusions. Techniques and anaesthetic agents have improved dramatically over the years...making the procedure much less uncomfortable than most patients fear.Tuesday, July 7, 2009
What is VEGF-trap
VEGF-trap is a drug currently being investigated for the treatment of "wet" macular degeneration. As with Lucentis...it needs to be injected into the vitreous cavity...at a frequency yet to be determined...but in the four to six week range...also much like Lucentis. Much future study is still required to determine the efficacy and safety of this drug. Approval...if it is to occur at all...will not be for several years.
Wednesday, June 24, 2009
Who is Donald K. Johnson?


Donald K. Johnson is a Canadian philanthropist who was born and raised in Lundar, Manitoba. He currently resides in Toronto, Ontario.
Johnson received a BScEE from the University of Manitoba in 1957 and an MBA from the Ivey Business School in 1963. His initial career was in electrical engineering with Canadian General Electric in Toronto and Federal Electric Corporation on the DEW line in the Canadian Arctic.
Johnson began his career in the investment industry in 1963 when he joined Burns Bros. & Denton Ltd. Since then he has held a series of management positions in Institutional Equity, Sales, Trading, Research, International, Retail and Investment Management. He was President of Burns Fry (1984-1989), and Vice-Chairman, Investment Banking, for BMO Nesbitt Burns and predecessor companies (1989-2004). Mr. Johnson continues as a Senior Advisor at BMO Nesbitt Burns.
Johnson's activity in the non-for-profit sector is extensive. He serves on the Advisory Board of the Richard Ivey School of Business at the [[University of Western Ontario, and is a member of the Board of Trustees of the Toronto General and Western Hospital Foundation and Chairman of its Vision Campaign, a $15 million campaign for the Donald K. Johnson Eye Centre at The Toronto Western Hospitall. He is Chairman Emeritus and director of the Council for Business and the Arts in Canada, a trustee of the Toronto Foundation for Student Success, a director of the Canadian Club of Toronto, and a member of the 2005 Major Individual Gifts Campaign Cabinet of the United Way of Greater Toronto. He is a past board member of the National Ballet of Canada, the Bishop Strachan School Foundation, and was Chairman of the Investment Dealers Association and a Governor of the Toronto Stock Exchange. In 1996-97 Johnson chaired a successful $13 million capital campaign for the National Ballet to build a new home for the Company in Toronto. Johnson has played the lead role on behalf of the charitable sector in Canada in lobbying the federal government to remove tax barriers for gifts of publicly listed securities to registered charities. His efforts over many years met with success first in 1997 when the Canadian government cut the capitals gains tax for such gifts in half, and then further in 2007 when the tax was eliminated entirely.
Johnson is a recipient of the Outstanding Volunteer Award, Association of Fundraising Professionals (1997), Friends of the Association of Gift Planners (1997), Richard Ivey School of Business Distinguished Service (1998) and the Arbor Award for Outstanding Volunteer Service to the University of Toronto (1999).
Johnson was appointed a Member of the Order of Canada in 2005.
What is Densiron?
Densiron is a "heavy Silicone Oil" (composed of a mixture of polydimethylsiloxane and perfluorohexyloctane). It is a clear and colourless oil which is used to repair complicated retinal detachments in the lower portions of the eye. This "heavy" liquid is heavier than water...and thus sinks down...and keeps pressure on the lower portions of the retina...allowing time for laser burns to firmly adhere the retina.Thursday, May 7, 2009
Which is better...Avastin or Lucentis?


Both drugs are anti-VEGF drugs (vascular endothelial growth factor)...which means they block a factor produced by the body called VEGF. VEGF stimulates the growth and leakage of blood vessels...so these drugs block the growth and leakage from these blood vessels. Such abnormal blood vessel growth and leakage can occur in a variety of retinal conditions...such as "wet" macular degeneration, diabetes, vein occlusions and many other conditions.
Lucentis has been specifically engineered for use in the eye...and as such, has been extensively tested both for efficacy and for safety. Avastin, which is a much larger molecule...is actually a drug for metastatic colon cancer...it has however been discovered...in "off label" use...to also be effective for a number of these condtions.
A study...initiated by the National Eye Institute, in Bethesda, Maryland (the CATT trial) is currently underway...comparing the two drugs. We anticipate some early data from this study perhaps in 2010 or 2011.
Sunday, April 19, 2009
Where is the Donald K. Johnson Eye Center?

The Donald K. Johnson Eye Center is located within the Toronto Western Hospital, The University Health Network, The University of Toronto. The address is 399 Bathurst Street, Toronto, Ontario, Canada. M5T 2S8. The Eye Center is located on the 4th, 6th and 7th Floors. Information can be obtained from the following two websites: www.tgwhf-uhn.ca/campaigns/dkjec/index.asp AND www.uhnophthlamology.com
What type of anaesthesia is required for retinal surgery?


Most adult patients are awake...but drowsy during retinal surgery. The anaesthetist will give sedatives intravenously...and the surgeon will freeze the eye with local anaesthetic. During the surgery...which typically takes between one and two hours...the patient will be drowsy but awake...and be aware of his or her surroundings. We want the patient to remain somewhat alert...because if the patient is too deep...they'll forget where they are and try to move (or climb off the operating room table!).
If a patient is claustrophobic...or just unable to contemplate being at all aware of the surgery...then general anaesthesia is used.