There is no absolute answer. Lucentis...blocks a chemical called "VEGF" (vascular endothelial growth factor) which is secreted in excess by the body in wet macular degeneration. VEGF causes abnormal blood vessels to grow and bleed...while Lucentis is in the eye...it blocks VEGF...and stops bleeding...once Lucentis is absorbed...the blood vessels tend to grow and bleed.
Different people however absorb Lucentis at different rates...so Lucentis stays inside the eye for different periods of time in different people. On average...Lucentis stays for approximately 28 days...so when Lucentis was first evaluated...it was re-injected every 28 days...we now however know...not surprisingly...that different people differ in how quickly or slowly they absorb Lucentis...and therefore...people differ in how frequently they need to be retreated with Lucentis.
The best approach if for the retinal specialist to follow each patient as an individual...by clinical examination and, as required...OCT and angiography...to individualize the treatment program best suited for each patient.
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